Cannabis for seizures/seizure disorders

Seizures are sudden changes in brain activity that can cause symptoms like confusion, staring, or shaking. The most common cause for seizures is epilepsy, a chronic brain disorder. But they can also be caused by brain injuries or infections.

Certain compounds in cannabis, particularly cannabidiol (CBD), may help treat seizures. Some research suggests that CBD can help calm brain activity so that seizures are less frequent and severe.

Research on cannabis for seizures

Only recently have researchers explored cannabis as a treatment for seizures. One major development is Epidiolex, a prescription medication approved by the Food and Drug Administration (FDA) that contains a purified form of CBD. It treats seizures related to Lennox-Gastaut syndrome and Dravet syndrome, two severe forms of epilepsy. Several clinical trials show that Epidiolex can help reduce seizures in people with these conditions.

Most studies around cannabis for seizures focus on CBD. Researchers are still exploring how other cannabis compounds may affect seizures. Cannabis’s long-term effects on seizures and whether it interacts with certain seizure medications are also unclear.

Using cannabis for seizures

Certain cannabis products may help reduce the frequency and severity of seizures. However, cannabis also has some risks and side effects. Speak with your doctor before using cannabis as a form of seizure treatment.

Benefits

CBD in cannabis may offer some benefits to people who have seizures, including:

• Fewer seizures:Studies show that CBD can help reduce the frequency of seizures, especially in cases where other treatments fail.
• Better quality of life: Some people who have seizures report general improvements in well-being after using cannabis. They also report fewer side effects compared to common seizure medications.
• Lower intake of medications: Common seizure medications like benzodiazepines can potentially cause serious side effects, including sedation and slow or shallow breathing. They can also lead to dependence. CBD may help reduce or replace the need for these medications. However, it’s essential to speak with your doctor before attempting to reduce or stop your medication.

Risks and side effects

As with any medication, medical cannabis and CBD have potential risks, such as:

• Side effects: Common cannabis side effects include drowsiness, lightheadedness, and appetite changes.
• Drug interactions: Cannabis can affect how your body processes other medications, including seizure medications.
• Potential pro-seizure effects: Some evidence suggests that high doses of tetrahydrocannabinol (THC), the main psychoactive compound in cannabis, may trigger seizures. Consider using high-CBD, low-THC products to help lower this risk.

Is it legal?

Cannabis laws differ depending on where you live. Some states allow full access to medical and recreational cannabis, while others impose strict regulations.

However, every state with a medical marijuana program lists epilepsy or seizures as a qualifying condition for a medical cannabis card.

Epidiolex is an FDA-approved prescription seizure medication that’s available in all 50 states.

More about seizures

A doctor will diagnose seizures using imaging tests and tests that measure brain activity. Many treatments can manage seizures, but refractory (drug-resistant) epilepsy is challenging to control with traditional methods.

Other treatments for seizures

You might need a combination of therapies to manage seizures effectively.

Traditional therapies

Different types of seizures require different treatments, or a mixture of several types of treatment. The most common treatments for seizures are:

• Antiepileptic Drugs (AEDs): These are the first choice for most people with seizures. Common AEDs include carbamazepine (Tegretol) and lamotrigine (Lamictal).
• Surgery: Surgery may be recommended to patients with focal seizures (seizures that occur in one part of the brain, and usually affect one side of the body).
• Vagus nerve stimulation (VNS): This is a device that sends electrical pulses to the brain to reduce seizures.

Natural and alternative therapies

Diet and lifestyle changes may reduce the number of seizures you experience, and improve your quality of life.

• Ketogenic diet: A high-fat, low-carb diet that has been shown to reduce seizures
• Herbal supplements: Some people use valerian or passionflower to control seizures due to their sedative effects, though evidence is limited
• Mind-body therapies: Techniques like yoga or meditation can help manage anxiety in those with epilepsy

Cannabis as part of your treatment plan for seizures

Medical cannabis could be a valuable addition to your treatment plan. CBD, in particular, may help reduce seizures, especially if other treatments haven’t worked.

Before trying cannabis, talk to your doctor, and consider applying for a medical cannabis card through Leafwell to access high-quality products at a licensed dispensary. Cannabis might improve your quality of life and work well with other treatments.

Frequently asked questions

There are several FAQs regarding medical cannabis and seizures.

Will marijuana help with seizures?

Research shows that medical cannabis may reduce the frequency of seizures, and make them less severe. Talk to your doctor if you want to use cannabis for seizures management.

Can CBD help seizures?

Yes, CBD has been shown to reduce seizure frequency, particularly for conditions like Lennox-Gastaut syndrome and Dravet syndrome.

How long does CBD take to work for seizures?

Research is still young, but one study on Lennox-Gastaut syndrome found that it can take a week of daily CBD use before the cannabinoid is fully effective against seizures.

What strain of marijuana is used for seizures?

Strains like Charlotte’s Web and ACDC, which are high in CBD and low in THC, are popular choices for managing seizures.

What type of CBD or medical cannabis product is best for seizures?

Oil-based CBD tinctures may be best due to their duration, onset time, and ease of use and dosing. However, what works best for one person may not work for you, so talk to your healthcare provider about choosing the best product for your needs.

Is medical marijuana legal for epilepsy?

In many states, epilepsy qualifies for medical marijuana use. Check your state’s laws to learn more.

Is there a difference between medical cannabis and Epidiolex for treating seizures and epilepsy?

Yes. Epidiolex is purified CBD extracted from cannabis. It does not contain any other cannabinoids, terpenes, or flavonoids. Cannabis, on the other hand, does contain other compounds and, therefore, may have different effects. Some cannabis compounds, like CBDV and THCA, have been shown to have antiseizure properties, but human trials are needed.

Can marijuana cause seizures?

Some research shows that cannabis products containing high doses of THC may trigger seizures. However, more research is needed to fully understand the risk of marijuana use and seizures.

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