Cannabis for depression

Depression is a leading mental health condition that affects how a person feels, thinks, and acts. Symptoms include persistent sadness, loss of interest in activities, fatigue, and trouble sleeping.

Some people turn to medical cannabis to help manage depression symptoms. Cannabis may promote relaxation and improve mood, and some research suggests it may offer benefits to people with depression.

Research on cannabis for depression

Some research suggests that low doses of tetrahydrocannabinol (THC) and cannabidiol (CBD), the two main compounds in cannabis,  may help regulate mood and stress. A review of both animal and human trials found that CBD may help manage anxiety, depression, and psychotic disorders.

In a self-reported survey study, people with depression reported significant improvements in their symptoms. Participants noted that high-CBD, low-THC strains were particularly effective for improving mood. The researchers also pointed out that long-term cannabis use can lead to tolerance, potentially reducing its effectiveness over time.

At the same time, medical cannabis may help some people lower their use of antidepressants and sedatives like benzodiazepines, which can have unwanted side effects.

Overall, studies on cannabis for depression are limited. While research generally suggests that cannabis can help with depression, some studies show the opposite, which is why more, larger studies are needed.

Using cannabis for depression

Many people use cannabis for depression, but it may not be right for everyone. For some people, cannabis improves mood, sleep, and motivation, while others experience negative effects like increased anxiety. Finding the right strain, dosage, and product type can make a big difference.

Benefits

Some potential benefits of cannabis for depression include:

• Mood regulation: Cannabinoids like CBD and THC interact with your body’s endocannabinoid system, which plays a role in mood and emotions.
• Reduced stress and anxiety: Some strains, particularly those with higher CBD content, may lower stress levels.
• Improved sleep: Cannabis may help with insomnia, which is a common symptom of depression.
• Increased motivation and focus: Certain strains can help boost energy and focus, easing depression.

Risks and side effects

Like any medication, medical cannabis may have side effects, including:

• Increased anxiety or paranoia: For some people, high-THC strains can make anxiety worse.
• Cognitive impairment: Cannabis may negatively affect short-term memory and concentration, especially with heavy use.
• Dependence or withdrawal symptoms: Regular use may lead to dependence.
• Interactions with other medications: Cannabis may interact with antidepressants or other medications, increasing the risk of side effects.

Is it legal?

The legal status of cannabis varies by state, and not all states that have legalized medical cannabis consider depression a qualifying condition for a medical card.

Alabama is the only state that lists depression as a qualifying condition, while Missouri lists “debilitating psychiatric disorders,” which could include major depression.

Minors with depression may be able to access medical cannabis through a registered caregiver. However, minors usually require two physicians’ recommendations, depending on state laws.

More about depression

Depression can be caused by a combination of genetic, biological, environmental, and psychological factors. Major depression is one of the most common mental illnesses in the U.S., affecting about 21 million (8.3%) Americans every year.

While some people can recover with conventional treatment, others may experience chronic depression that requires long-term management.

Other treatments for depression

There are several treatment options for depression. While some people find relief through cannabis, others may benefit from traditional or alternative therapies.

Traditional therapies

Common forms of depression treatment include:

• Antidepressant medications: Common antidepressant medications include SSRIs, SNRIs, and tricyclic antidepressants.
• Psychotherapy: Cognitive-behavioral therapy (CBT) and other forms of talk therapy can be effective.
• Lifestyle changes: Regular exercise, a healthy diet, and good sleep hygiene can help manage depression.

Natural and alternative therapies

Complementary treatments can help manage some of the symptoms of depression.

• St. John’s Wort: This herbal supplement may help mild-to-moderate depression.
• Mindfulness and meditation: These practices can help reduce symptoms of depression, including stress.
• Acupuncture:  This ancient practice may support other treatments in managing depression.
• Light therapy: This may be helpful for people who have seasonal affective disorder (SAD), also known as seasonal depression.

Cannabis as part of your treatment plan for depression

Medical cannabis may be an option for some people with depression, but it should be part of a comprehensive treatment plan. Always consult a healthcare professional before using cannabis, especially if you’re taking other medications.

In many states, medical cannabis cards are required to legally access cannabis. Leafwell can help you get your medical card online through our telehealth services, with a team of healthcare professionals who can guide you toward symptom relief.

Frequently asked questions

Here are answers to FAQs about using cannabis for depression.

Can cannabis make depression worse?

For some people, high doses may increase anxiety or worsen depression symptoms, especially if they’re sensitive to THC. Choosing the right strain and dosage is important.

Is marijuana a natural antidepressant?

Maybe. For some people, cannabis relieves depression symptoms. Some studies show that cannabis has mood-boosting properties that may relieve depression.

Is CBD or THC better for depression?

That depends on the individual. Some people prefer CBD because of its calming effects and the fact that it’s not intoxicating., Others prefer THC because of its mood-boosting effects. For some people, a balanced ratio may work best.

How long does it take for CBD to help depression?

If you’re using CBD for depression, it can take up to 2 weeks to feel its full effects.

Can you get a medical marijuana card for depression?

That depends on where you live. Depression is a qualifying condition for medical marijuana in Alabama. In other states, you may qualify through a related condition like PTSD or chronic pain.

Is it safe for minors to use cannabis for depression?

Maybe. Cannabis may negatively affect adolescent brain development and put a minor at risk of cannabis use disorder. Teenagers with depression should consider more traditional treatment methods if possible.

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