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Explore A-Z conditions
Constipation
Cannabis for Constipation
Constipation is when you find it hard to move your bowels or you go to the toilet less often than usual. Around 16 out of 100 U.S. adults have constipation, and it is one of the most common digestive problems in the US.
Cannabinoids and the endocannabinoid system (ECS) are heavily involved in digestion and keeping the stomach in balance. Alongside the brain & spinal cord, the digestive system contains one of the largest concentrations of cannabinoid receptors in the human body. An out-of-balance ECS can cause digestive problems of all sorts, including both diarrhea and constipation. Cannabinoids can “reset” the digestive system. “In a nationally representative sample of U.S. adults, recent users of marijuana had 32% lower odds of constipation compared with past or never users.”
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Animal Study
3
Clinical Trial
3
Double Blind Clinical Trial
1
Meta-analysis
11
Total studies
Constipation
18
Positive
10 studies
56%
Inconclusive
5 studies
28%
Negative
3 studies
17%
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Relevant studies
The information in our comprehensive A to Z encyclopedia comes from real scientific studies.
Uncover the detailed results of these studies and find out how effective medical marijuana is for dozens of conditions.
- 2-Arachidonoyl glycerol suppresses gastric emptying via the cannabinoid receptor 1-cholecystokinin signaling pathway in mice
- AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner
- A Rare Case of Cannabinoid Hyperemesis Syndrome Secondary to Cannabidiol for Refractory Epilepsy
- Cannabidiol: Bridge between Antioxidant Effect, Cellular Protection, and Cognitive and Physical Performance
- Cannabinoids and Gastrointestinal Motility: Pharmacology, Clinical Effects, and Potential Therapeutics in Humans